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GDC-0834

Cat. No. :YN440316

  • CAS No. :1133432-49-1

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    • Products Infomation
    • Biological Activity
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    • Product Name:GDC-0834
      CAS NO.:1133432-49-1
      Chemical Name:
      Synonyms:
      Molecular Weight:596.74
      Molecular Formula:C₃₃H₃₆N₆O₃S
      SMILES:O=C(C1=CC(CCCC2)=C2S1)NC3=CC=CC(C(N=C4NC5=CC=C([C@H]6N(C)CCN(C)C6=O)C=C5)=CN(C)C4=O)=C3C
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:GDC-0834 is a potent and selectiveBTKinhibitor. GDC-0834 inhibits BTK with an in vitroIC50 of 5.9 and 6.4nM in biochemical and cellular assays, respectively, and in vivoIC50 of 1.1 and 5.6μM in mouse and rat, respectively.
      IC50&Target:
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