CNX-500
Cat. No. :YN440007
CAS No. :1202758-21-1
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order@ubiochem.com| Product Name: | CNX-500 |
| CAS NO.: | 1202758-21-1 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 961.18 |
| Molecular Formula: | C₄₈H₆₈N₁₀O₉S |
| SMILES: | O=C(NCCCOCCOCCOCCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)CCCC(NCCCOC3=CC=CC(NC4=NC=C(C)C(NC5=CC=CC(NC(C=C)=O)=C5)=N4)=C3)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CNX-500 is a probe consisting of a covalentBtkinhibitor (CC-292) chemically linked to biotin. CNX-500 retains inhibitory activity against Btk(IC50 of 0.5nM) and the ability to form a covalent bond withBtk. CNX-500 has low inhibitory effects on kinase epidermal growth factor receptor, and upstream Src-family kinases including Syk and Lyn. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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