Leptomycin B
Cat. No. :YN360593
CAS No. :87081-35-4
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5mg
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Product Name: | Leptomycin B |
CAS NO.: | 87081-35-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 540.73 |
Molecular Formula: | C₃₃H₄₈O₆ |
SMILES: | O=C(O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(CC)C=C[C@H]1[C@@H](C)C=CC(O1)=O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivatesCRM1/exportin 1by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle. |
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