Eltanexor Z-isomer
Cat. No. :YN360031
CAS No. :1642300-78-4
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Product Name: | Eltanexor Z-isomer |
CAS NO.: | 1642300-78-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 428.29 |
Molecular Formula: | C₁₇H₁₀F₆N₆O |
SMILES: | O=C(N)/C(C1=CN=CN=C1)=CN2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Eltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor. IC50: In Vitro: Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100nM-50μM, < 100nM, > 30μM, respectively. In Vivo: |
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References: |
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