Leptomycin A
Cat. No. :YN361008
CAS No. :87081-36-5
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order@ubiochem.com| Product Name: | Leptomycin A |
| CAS NO.: | 87081-36-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 526.70 |
| Molecular Formula: | C₃₂H₄₆O₆ |
| SMILES: | O=C(O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(C)C=C[C@H]1[C@@H](C)C=CC(O1)=O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Leptomycin A, a Streptomyces metabolite, is an inhibitor ofCRM1 (exportin 1)that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B. |
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