YN360858 (-)-Sparteine sulfate pentahy... 6160-12-9

Sparteine Sulfate, a quinolizidine alkaloid, is the sulfate form of sparteini, which is a sodium channel blocker used as an oxytocic and an anti-arrhythmia agent.

YN350241 Tomatidine hydrochloride 6192-62-7

A steroidal alkaloid that suppresses NF-κB signaling in LPS-stimulated macrophages, blocking induced expression of iNOS and COX-2; functional inhibitor of acid sphingomyelinase; antibacterial against S. aureus variants; preve...

YN370698 (3-Carboxypropyl)trimethylamm... 6249-56-5

(3-Carboxypropyl)trimethylammonium chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.

YN321659 Oxprenolol hydrochloride 6452-73-9

Oxprenolol is a non-selective beta blocker with some intrinsic sympathomimetic activity.

YN372843 Pentoxifylline 6493-05-6

Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity.

YN481991 Hydrastinine 6592-85-4

Hydrastinine is a major alkaloid constituent in goldenseal (Hydrastis canadensis). Hydrastinine can be used as a haemostatic agent.

YN371108 ML171 6631-94-3

2-Acetylphenothiazine (ML171) is a potent and selective inhibitor of NADPH-oxidase with IC50s of 0.25 μM, 5 μM, 3μM, 5 μM and 5.5 μM for NOX1, NOX2, NOX3, NOX4 and xanthine oxidase, respectively.

YN320525 Practolol 6673-35-4

Practolol is a potent and selectiveβ1-adrenergic receptorantagonist. Practolol can be used for the research of cardiac arrhythmias .

YN482023 Perhexiline maleate 6724-53-4

Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50 of 77 μM and 148 μM for rat heart CPT1 and liver CPT1, respectively.

YN482769 Isorhamnetin 3-O-galactoside 6743-92-6

Isorhamnetin 3-O-galactoside (Cacticin), a flavonoid glycoside isolated fromArtemisia capillarisThunberg, which ameliorates CCl4-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory si...

YN482718 Mesaconine 6792-09-2

Mesaconinean, an ingredient fromAconitum carmichaeliiDebx., has cardiac effect.

YN372543 GW4869 6823-69-4

GW4869 is a noncompetitiveneutral sphingomyelinase (N-SMase)inhibitor with an IC50 of 1μM. GW4869 is an inhibitor ofexosomebiogenesis/release.

YN483200 Lotusine 6871-67-6

Lotusine is a pure alkaloid extracted from the green seed embryo ofNelumbo nucifera Gaertn. Lotusine shows effects on the action potentials in myocardium and slow inward current in cardiac Purkinje fibers.

YN321772 Arborine 6873-15-0

Arborine, isolated fromGlycosmis arborea, inhibits the peripheral action of acetylcholine and induces a fall in blood pressure.

YN330172 DMNQ 6956-96-3

DMNQ is a redox cycling agent that generates both superoxide and hydrogen peroxide intracellularly in a concentration dependent manner. DMNQ increasesROSgeneration.

YN330641 Bixin 6983-79-5

Bixin (BX), isolated from the seeds ofBixa orellana, is a carotenoid, possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation an...

YN482460 DL-Arginine 7200-25-1

Arginine is an α-amino acid that is used in the biosynthesis of proteins and plays an important role in cell division, wound healing, removing ammonia from the body, immune function, and the release of hormones.

YN480152 Hepronicate 7237-81-2

Hepronicate is a peripheral vasodilator with blood lipid lowering action.

YN483518 Dihydralazine sulfate 7327-87-9

Dihydralazine sulphate is a dihydralazine-l,4-phthalazine derivative and used as an antihypertensive drug.

YN373250 Araloside A 7518-22-1

Araloside A (Chikusetsusaponin IV) is a component ofPanax japonicus, with low-renin-inhibitory activity, with an IC50 of 77.4μM.