YN482352 Vitexin 3681-93-4

An apigenin flavone C-glycoside isolated from various tropical plant species that demonstrates broad antioxidant, anti-inflammatory, anticancer, and antinociceptive activities

YN360356 Disopyramide 3737-09-5

Disopyramide is a class IA antiarrhythmic drug which acts via blockade of sodium channels depressing phase 0 of the action potential. Disopyramide possesses significant negative inotropic, anticholinergic effects and enhances AV nodal...

YN481875 Fenobucarb 3766-81-2

Fenobucarb is an extensively used carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk fa...

YN321597 Todralazine hydrochloride 3778-76-5

Todralazine hydrochloride (Ecarazine hydrochloride) is an anti-hypertensive agent, acts as aβ2ARblocker, with antioxidant and free radical scavenging activity.

YN251772 Neamine 3947-65-7

Neamine is a non-toxic derivative derivative of Neomycin and is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targetingangiogenin. Neamine has potent antibacterial, antitumor and neuroprotective a...

YN270048 PD146176 4079-26-9

PD146176 (NSC168807), a15-Lipoxygenase (15-LO)inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197nM, IC50=0.54μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy i...

YN410118 Stachydrine hydrochloride 4136-37-2

Stachydrine is isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits. It has potent anti-metastatic activity and cardioprotective effects.

YN360920 Catharanthine Tartrate 4168-17-6

Catharanthine hemitartrate is the starting material for the synthesis of the antitumor drugs vinblastine and vincristine.

YN321538 (S)-(-)-Propranolol hydrochl... 4199-10-4

(S)-(-)-Propranolol hydrochloride, the active enantiomer of propranolol, is a β-Adrenoceptor (β-Adrenergic Receptor) antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively.

YN482070 Tolonidine 4201-22-3

Tolonidine is a derivative of imidazoline. Tolonidine is orally active and has been shown to possess hypotensive and antihypertensive properties.

YN321487 Clonidine hydrochloride 4205-91-8

Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.

YN270243 Cladribine 4291-63-8

Cladribine is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.

YN480079 Didesethyl chloroquine 4298-14-0

Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial drug Chloroquine. Didesethyl chloroquine is a potent myocardial depressant.

YN360853 Ajmaline 4360-12-7

Ajmaline is an alkaloid that is class Ia antiarrhythmic agent.

YN280129 Ligustilide 4431-01-0

Ligustilide may have the neuroprotective potential of Ligustilide in cerebral ischemic damage via antioxidant and anti-apoptotic properties. Ligustilide and senkyunolide A have vasorelaxation activities in contractions to various contra...

YN320809 Angiotensin II human 4474-91-3

Angiotensin II human is converted by Angiotensin I through removal of two C-terminal residues by the enzyme angiotensin-converting enzyme (ACE). Angiotensin II is mediated by AT1 and AT2 receptors, which are seven transmembr...

YN360229 NSC 15364 4550-72-5

NSC 15364 (compound 59) is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization, concomitant with an inhibition of apoptosis.

YN373254 N-Nornuciferine 4846-19-9

N-Nornuciferine is an aporphine alkaloid in lotus leaf that significantly inhibitsCYP2D6with IC50 and Kiof 3.76 and 2.34μM, respectively.

YN372889 Vinburnine 4880-88-0

Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.

YN481990 Hydrastinine hydrochloride 4884-68-8

Hydrastinine hydrochloride is a major alkaloid constituent in goldenseal (Hydrastis canadensis). Hydrastinine hydrochloride can be used as a haemostatic agent.