Chemical structure
Cat.No.
Product Name
CAS no.
Target
TA-01 is a potentCK1 and p38 MAPKinhibitor, with IC50s of 6.4nM, 6.8nM, 6.7nM for CK1ε, CK1δ and p38 MAPK, respectively.
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM. TA-02 especially inhibits TGFBR-2.
Pz-1 is a potentRET and VEGFR2 inhibitor with IC50s of less than 1nM for both wild type kinases.
YN484117 Atrial Natriuretic Peptide ... 1815618-06-4
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for...
YN484110 Brain Natriuretic Peptide-4... 1816939-52-2
Brain Natriuretic Peptide-45, mouse (BNP-45, mouse) is a circulating form of mouse brain natriuretic peptide isolated from mouse heart with potent hypotensive and natriuretic potency.
SKA-121 is a selectiveKCa3.1activator. SKA-121 exhibitsEC50s of 109nM and 4.4μM forKCa3.1 and KCa2.3, respectively.
MM 07 is a biasedapelin receptoragonist, with aKDof 300nM in CHO-K1 cells and aKDof 172nM in human heart.
YN320608 Terlipressin acetate 1884420-36-3
Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selectivevasopressin V1 receptoragonist that reduces the splanchnic blood flow and portal pressure and controls acute ...
YN350122 ERK5-IN-2 1888305-96-1
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50 of 0.82 μM and 3 μM for ERK5 and ERK5 MEF2D, respectively.
YN290078 Pparδ agonist 1 1902161-12-9
Pparδ agonist 1 is aPPAR-δagonist, with an EC50 of 5.06nM, used in the research of PPAR-delta related diseases, such as mitochondrial diseases, muscular diseases, vascular diseases, demyelinating diseases and metabolic disea...
NTP42 is athromboxane A2 (TXA2) receptorantagonist with an IC50 of 3.278nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46609. NT...
VBIT-4 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 17μM. VBIT-4, as anapoptosisinhibitor, can be used for therapeutic purposes in apoptosis-associated disorders...
YN290152 SRPKIN-1 2089226-94-6
SRPKIN-1 is a covalent and irreversibleSRPK1/2inhibitor with IC50s of 35.6 and 98nM, respectively. Anti-angiogenesis effect.
R-IMPP is an inhibitor of PCSK9 secretion, half maximal inhibitory concentration [IC50] = 4.8 μM.
HS-1371 is a potent RIP3 kinase inhibitor with an IC50 of 20.8 nM. It binds to the ATP binding pocket of RIP3 and inhibits ATP binding to prevent RIP3 enzymatic activity in vitro.
YN371384 Lp-PLA2-IN-3 2196245-16-4
Lp-PLA2-IN-3 is a potent and orally bioavailablelipoprotein-associated phospholipase A2 (Lp-PLA2)inhibitor, with an IC50 of 14nM for recombinant human Lp-PLA2 (rhLpPLA2).
YN484059 ELA-21 (human) 2245073-05-4
ELA-21 (human) is anapelin receptoragonist with a pKi of 8.52. ELA-21 (human) completely inhibits Forskolin-induced cAMP production and stimulates β-arrestin recruitment with subnanomolar potencies. ELA-21 (human) is an ago...
YN280076 (3S,5R)-Fluvastatin D6 2249799-34-4
(3S,5R)-Fluvastatin D6 is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductaseinhibitor with an IC50 of 8nM. Fluvastatin protects vascular smooth muscle ce...
YN372222 (3S,5R)-Fluvastatin D6 sod... 2249799-35-5
(3S,5R)-Fluvastatin D6 sodium is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductaseinhibitor with an IC50 of 8nM. Fluvastatin protects vascular smooth m...
Ned-K is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Ned-K is effective at dampening simulated ischaemia and reperfusion (sIR)-induced Ca2+oscillations in cardiomyocytes.
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