YN360733 Minoxidil 38304-91-5

Minoxidil (U10858) is anATP-sensitive potassium (KATP) channelopener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of...

YN321619 Penbutolol sulfate 38363-32-5

N/A

YN482575 Benzoylpaeoniflorin 38642-49-8

Benzoylpaeoniflorin is a natural product; may treat coronary heart disease by decreasing apoptosis.

YN373337 Resveratroloside 38963-95-0

Resveratroloside is a competitive inhibitior ofα-glucosidasewith an IC50 of 22.9μM. Resveratroloside has the ability to regulate PBG (postpr and ial blood glucose) levels. Resveratroloside exhibits cardioprotective effect.

YN270453 Asperosaponin VI 39524-08-8

Asperosaponin VI, A saponin component fromDipsacus asperwall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bc...

YN484215 Nicotinoyl cyclandelate 39537-99-0

Nicotinoyl cycl and elate can be used to lower the perfusion pressure of cerebral blood vessels and the blood pressure of femoral artery.

YN320195 (±)-Befunolol 39552-01-7

(±)-Befunolol is aβ-adrenoceptorblocking agent.

YN360785 Nitrendipine 39562-70-4

Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.

YN360265 SKA-31 40172-65-4

SKA-31 is a potentpotassium channelactivator with EC50s of 260nM, 1.9μM, 2.9μM, and 2.9μM forKCa3.1,KCa2.2,KCa2.1 and KCa2.3, respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and...

YN480286 IQB-782 40454-21-5

IQB-782 is a cysteine derivative. IQB-782 has inhibition forthrombin activatable fibrinolysis inhibitor (TAFI), with anKi(app) of 0.14μM. IQB-782 shows a potent mucolytic-expectorant activity.

YN484189 Indanazoline 40507-78-6

Indanazoline (as monohydrochloride active substance of Farial) is characterized by a pronounced vasoconstrictive action.

YN484237 CS476 41177-35-9

CS476 is a potent hypoglycaemic agent.

YN370944 Resorcinolnaphthalein 41307-63-5

Resorcinolnaphthalein is a specificangiotensin-converting enzyme 2 (ACE2)enhancer and activates ACE2 activity with an EC50 value of 19.5μM. Resorcinolnaphthalein can be used for the investigation of hypertension and renal f...

YN360488 NP118809 41332-24-5

NP118809 is a potentN-type calcium channelblocker, with an IC50 of 0.11μM; also less potently inhibitsL-type calcium channelwith an IC50 of 12.2μM.

YN321434 L-(-)-α-Methyldopa hydrate 41372-08-1

L-(-)-α-Methyldopa (Methyldopa, MK-351) hydrate, a potent antihypertensive drug, is a selective agonist for α2-adrenergic receptors.

YN482951 Turkesterone 41451-87-0

Turkesterone, isolated fromAjuga turkestanica, is a potent ecdysteroid. Turkesterone acts as anecdysteroid receptor(EcR) agonist in some insect systems.

YN290507 Bezafibrate 41859-67-0

Bezafibrate is the first clinically tested dual and pan-PPAR co-agonism.

YN321856 D[LEU4,LYS8]-VP 42061-33-6

D[LEU4,LYS8]-VP is a selective agonist ofvasopressin V1breceptor, with theKisof 0.16nM, 0.52nM, and 0.1.38nM for rat, human and mouseV1breceptor, respectively. D[LEU4,LYS8]-VP has weak antidiuretic, vasopressor, ...

YN321582 Nadolol 42200-33-9

Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.

YN360416 Vinpocetine 42971-09-5

Vinpocetine is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia and Alzheimer's disease.