YN360172 Almokalant 123955-10-2

Almokalant is a class III antiarrhythmic drug, acts as apotassium channelblocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+current.

YN483236 Alcesefoliside 124151-38-8

Alcesefoliside is a flavonoid isolated fromNitraria sibiricaPall, with antioxidant activity.

YN320641 Losartan Carboxylic Acid 124750-92-1

Losartan Carboxylic Acid (E-3174, EXP-3174), an active carboxylic acid metabolite of Losartan, is a non-peptide angiotensin II (AT1) receptor antagonist. Losartan Carboxylic Acid inhibits the specific binding of [125I]-angio...

YN321157 Losartan potassium 124750-99-8

Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

YN483878 AP 811 124833-45-0

AP 811 is a selective atrial natriuretic peptide clearance receptor(APN-CR, NPR3)antagonist (Ki=0.48nM). AP 811 displays >20,000-fold selectivity for NPR3 over NPR1. AP 811 abolishes ANP-induced pump stimulation.

YN481654 Ro-24-4736 125030-71-9

Ro 24-4736 is a potent, selective, p.o.-active platelet-activating factor (PAF) antagonist with a long duration of action.

YN372528 NSP-805 125068-54-4

NSP-805 is a potent and selective inhibitor of guinea pig cardiacphosphodiesterase 3 (PDE3), and a cardiotonic agent with vasodilator properties.

YN373992 5-Lipoxygenase-In-1 125235-15-6

5-Lipoxygenase-In-1 is a5-Lipoxygenaseinhibitor extracted from patent EP 331232 A2, table 4, compound example 4.10.

YN310250 Ro 31-8220 125314-64-9

Ro 31-8220 is a potentPKCinhibitor, with IC50s of 5, 24, 14, 27, 24 and 23nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b...

YN483800 Fibronectin Adhesion-promoti... 125720-21-0

Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (M...

YN480174 (E)-Alprenoxime 125720-84-5

(E)-Alprenoxime is the isomer of the Alprenoxime. Alprenoxime is a site-activated ocularβ-blocker.

YN481212 Atorvastatin acetonide tert-b... 125971-95-1

Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blo...

YN360035 BAPTA-AM 126150-97-8

BAPTA-AM is a well-known membrane permeableCa2+chelator. BAPTA-AM inhibitsh ERG channels,hKv1.3 and hKv1.5channels in HEK 293 cells with IC50s of 1.3μM, 1.45μM and 1.23μM, respectively.

YN321851 Sarafotoxin S6a 126738-34-9

Sarafotoxin S6a, a sarafotoxin analogue, is aendothelin receptoragonist  and has anETA/ETBselectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a elicits the pig coronary artery with an EC50 value o...

YN373496 N-Acetyl-Ser-Asp-Lys-Pro 127103-11-1

N-Acetyl-Ser-Asp-Lys-Pro, an endogenous tetrapeptide secreted by bone marrow, is a specific substrate for the N-terminal site ofACE.

YN330657 Chitoheptaose heptahydrochlor... 127171-89-5

Chitoheptaose heptahydrochloride is a chitosan oligosaccharide with antioxidant, anti-inflammatory, antiapoptotic and cardioprotective activities. Chitoheptaose heptahydrochloride significantly enhances the growth and photosynthesis p...

YN360214 Y-27152 127408-30-4

Y-27152, a prodrug of the KATP(Kir6) channel opener Y-26763, is a long-actingK+ channelopener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state.

YN360067 Y-26763 127408-31-5

Y-26763 is aK+channelopener and active metabolite of Y-27152. Y-26763 is an ATP-sensitive K+(KATP) channel activator.

YN322047 KF 13218 127654-03-9

KF 13218 is a potent, selective and long lastingthromboxane B2(TXB2) synthase inhibitor with an IC50 value of 5.3±1.3nM.

YN321880 C-Type Natriuretic Peptide... 127869-51-6

C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide. C-type natriuretic peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance...