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Cardiovascular Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN321913 [Leu31,Pro34]-Neuropeptide ... 132699-73-1

    [Leu31,Pro34]-Neuropeptide Y(human,rat) is a specificneuropeptide Y Y1receptoragonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) slao inhibits Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) can increase blood pressure in ane...

  • YN320996 YS-49 132836-42-1

    YS-49 is aPI3K/Akt(a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibitsangiotensin II (Ang II)-stimulated proliferation of VSMCs via induct...

  • YN360817 Lercanidipine hydrochloride 132866-11-6

    Lercanidipine is a calcium channel blocker of the dihydropyridine class.

  • YN321241 BIBS 39 133085-33-3

    BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.

  • YN480675 Ibrolipim 133208-93-2

    Ibrolipim (NO-1886) is an orally activelipoprotein lipase (LPL)-promoting agent. Ibrolipim decreases plasma triglycerides, increases high-density lipoprotein cholesterol levels. Ibrolipim has renoprotective and hypolipidemic effec...

  • YN480107 AM-92016 hydrochloride 133229-11-5

    AM-92016 hydrochloride is a specific blocker of rectifier potassium current (IK). AM-92016 hydrochloride delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse thereby...

  • YN321953 Brain Natriuretic Peptide (... 133448-20-1

    Brain Natriuretic Peptide (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).

  • YN370076 Revizinone 133718-29-3

    Revizinone is a novel selective phosphodiesterase (PDE) inhibitor with IC50 values on this enzyme to 0.036 microM.

  • YN370077 R 80123 133718-30-6

    R 80123 is the Z-isomer of R 79595, is also a highly selective phosphodiesterase inhibitor. The fuction is similar to R 80122 (HY-100615, Revizinone). In vivo: The administration of Revizinone improved the haemodynamic profile wi...

  • YN360021 Caldaret 133804-44-1

    Caldaret is an intracellular Ca2+ h and ling modulator that acts through reverse mode Na+/Ca2+ exchangerinhibition.

  • YN484070 Nattokinase 133876-92-3

    Nattokinase is a potent fibrinolytic enzyme. Nattokinase can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Nattokinase can be used for the research of cardiovascular diseases.

  • YN373454 Leucylarginylproline 133943-59-6

    Leucylarginylproline is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 0.27μM.

  • YN361064 U89232 134017-78-0

    U-89232 appears to be a cardioselectiveKATPchannel opener.

  • YN484039 YRGDS Fibronectin Fragm... 134282-68-1

    YRGDS Fibronectin Fragment is a fibronectin fragment, an adhesion peptide that displays strong binding affinity to thrombin-stimulated platelets.

  • YN320291 Sarpogrelate hydrochloride 135159-51-2

    Sarpogrelate is a selective 5-HT2A antagonist with pKi values of 8.52, 7.43 and 6.57 for 5-HT2A, 5-HT2C and 5-HT2B receptors respectively.

  • YN372394 RP-64477 135239-65-5

    RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT). RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestina...

  • YN320184 CGP48369 135689-23-5

    CGP48369 is a nonpeptidicangiotensin II receptorantagonist, used for anti-hypertensive research.

  • YN321837 MDL 29913 135721-56-1

    MDL 29913, a cyclic pseudopeptide, is a competitiveNK2tachykinin receptor selective antagonist, with a pA2of 8.66.

  • YN321328 Palonosetron 135729-61-2

    Palonosetron is a 5-HT3 antagonist with Ki value of 0.17 nM. It is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

  • YN321331 Palonosetron Hydrochloride 135729-62-3

    Palonosetron HCl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.

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