FR 180204
Cat. No. :YN350107
CAS No. :865362-74-9
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order@ubiochem.com| Product Name: | FR 180204 |
| CAS NO.: | 865362-74-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 327.34 |
| Molecular Formula: | C₁₈H₁₃N₇ |
| SMILES: | NC1=NNC2=NN=C(C3=C4C=CC=CN4N=C3C5=CC=CC=C5)C=C21 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | FR 180204 is an ATP-competitive, selective ERK inhibitor with Ki of 0.31 μM and 0.14 μM for ERK1 And ERK2, respectively. It is 30-fold less potent against the related kinase p38α and failed to inhibit any kinases(MEK1, MKK4, IKKα, PKCα, Src, Syc, and PDGFα) at less than 30 μM. |
| IC50&Target: | |
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| In Vivo: | |
| Clinical Trial: | |
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