HSP27 inhibitor J2
Cat. No. :YN371005
CAS No. :2133499-85-9
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Product Name: | HSP27 inhibitor J2 |
CAS NO.: | 2133499-85-9 |
Chemical Name: | |
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Molecular Weight: | 264.30 |
Molecular Formula: | C₁₃H₁₂O₄S |
SMILES: | O=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | HSP27 inhibitor J2 (J2) is aHSP27inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition. |
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