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HS-27

Cat. No. :YN371255

  • CAS No. :1562024-11-6

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    • Products Infomation
    • Biological Activity
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    • Product Name:HS-27
      CAS NO.:1562024-11-6
      Chemical Name:
      Synonyms:
      Molecular Weight:993.13
      Molecular Formula:C₅₂H₆₀N₆O₁₂S
      SMILES:O=C(N)C1=CC=C(N2N=C(C)C3=C2CC(C)(C)CC3=O)C=C1NCCCOCCOCCOCCOCCOCCCNC(NC4=CC5=C(C6(C7=C(OC8=C6C=CC(O)=C8)C=C(O)C=C7)OC5=O)C=C4)=S
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:HS-27, a fluorescently-tetheredHsp90inhibitor, assays surface Hsp90 expression on intact tissue specimens. HS-27 is made up of the core elements of SNX-5422, an Hsp90 inhibitor, tethered via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC), that binds to ectopically expressed Hsp90. HS-27 has potential use in a see- and -treat paradigm in breast cancer.
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