Chemical structure
Cat.No.
Product Name
CAS no.
Target
Luminescence Cell-Based Primary HTS to Identify Inhibitors of MITF
YN251789 Picropodophyllone 477-48-5
Picropodophyllone, an aryltetralin lignan, is isolated from leaves ofPodophyllum hex and rum, and has antifungal activities.
YN251658 Isochondrodendrine 477-62-3
Isochondrodendrine ( Isochondrodendrin) is a class of bisbenzylisoquinoline alkaloid isolated fromIsolona ghesquiereina. Isochondodendrine has strong antiplasmodial activity againstPlasmodium falciparum.
YN250165 Damnacanthal 477-84-9
Damnacanthal is an anthraquinone isolated from the root ofMorinda citrifolia. Damnacanthal is a highly potent, selective inhibitor ofp56lcktyrosine kinaseactivity. Natural Damnacanthal inhibitsp56lckautophosphorylation and phosphoryl...
Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects.
Eleutherol is a naphthalene isolated fromE. americanawithantifungalactivities. Eleutherol is against yeastsC and ida albicans,C. tropicalis,Saccharomyces cerevisiae and Cryptococcus neoformanswithMICvalues between 7.8 µg/mL and...
Pinocembrin is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and a...
Naringenin is a natural predominant flavanone derived from plant food, which is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune s...
YN251899 Phloracetophenone 480-66-0
Phloracetophenone (2,4,6-trihydroxyacetophenone) is the aglycone part of acetophenone glycoside obtained fromCurcuma comosaRoxb, with cholesterol-lowering activity. Phloracetophenone enhances cholesterol 7α-hydroxylase (CYP7A1) act...
YN330645 α-Spinasterol 481-18-5
α-Spinasterol, isolated fromSpinacia oleracea, has antibacterial activity. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive eff...
YN251734 Cepharanthine 481-49-2
Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.
YN251529 Isopimpinellin 482-27-9
Isopimpinellin and imperatorin have chemopreventive effects when administered orally on skin tumor initiation by 7,12-dimethylbenz[a]anthracene (DMBA). Isopimpinellin effectively inhibits mouse COH activity (IC50 values 19-40 mic...
Hyperoside, a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.
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