YN251589 Rhapontigenin 500-65-2

In vitro inhibitory concentration against proliferation of HL60 cells

YN251137 Proguanil 500-92-5

Proguanil is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.

YN251955 Kojic acid 501-30-4

Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 ?M for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.

YN310294 Resveratrol 501-36-0

Resveratrol has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases（LOX, IC50=2.7 μM）, kinases, sirtuins and other proteins. It has anti-cancer, anti-inflammatory, blood-sugar-loweri...

YN374242 Desaminotyrosine 501-97-3

Desaminotyrosine is a microbially associated metabolite protecting frominfluenzathrough augmentation oftype I interferonsignaling.

YN251252 Dixanthogen 502-55-6

Dixanthogen is an ectoparasiticide.

YN251920 3-Nitropropanoic acid 504-88-1

3-Nitropropionic acid (3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain.

YN251895 1,3-Dithiane 505-23-7

1,3-Dithiane is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon. 1,3-Dithiane is also a sulfur-containing Maillard reaction products (MRPs) found in boiled beef extracts. 1,3-Dithiane shows a p...

YN371119 2,3-Butanediol 513-85-9

2,3-Butanediol is a butanediol derived from the bioconversion of natural resources.

YN251726 Abietic acid 514-10-3

Abietic acid, an abietane diterpenoid, inhibited soybean 5-lipoxygenase with an IC50 of 29.5?±?1.29?μM.

YN251357 Sulfisomidin 515-64-0

Sulfisomidin is a sulfonamide antibacterial.

YN371102 Cycloguanil 516-21-2

Cycloguanil, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.

YN361011 Sennidin B 517-44-2

Sennidin B, a stereoisomer isolated from the leaves ofCassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibitsHCV NS3 helicase, with an IC50 of 0.8μM. Sennidin A induces phosphorylation of Akt and gl...

YN251708 Citrinin 518-75-2

Citrinin is a mycotoxin which causes contamination in the food and is associated with different toxic effects. Citrinin is usually found together with another nephrotoxic mycotoxin, Ochratoxin A. Citrinin is also reported to possess ...

YN251548 Tricin 520-32-1

Tricin is a natural flavonoid present in large amounts in rice bran. Tricin can inhibithuman cytomegalovirus (HCMV)replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregu...

YN251257 Dehydroacetic acid 520-45-6

Dehydroacetic acid is an organic compound, used mostly as a fungicide and bactericide.

YN251442 Physcion 521-61-9

Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of6-phosphogluconate dehydrogenase, with an IC50 and aKdof 38.5μM and 26.0μM, respectively. Phy...

YN251258 Broxyquinoline 521-74-4

Broxyquinoline is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes.

YN360806 Dequalinium Chloride 522-51-0

Dequalinium Chloride is a selective blocker of apamin-sensitive K+ channels.

YN250533 Ethylhydrocupreine 522-60-1

Ethylhydrocupreine (Optochin) is a quinine derivate with antimicrobial activity againstS. pneumoniae. Ethylhydrocupreine also possesses antimalarial activity againstPlasmodium falciparum, with an IC50 of 25.75nM. Ethylhydrocupreine...