YN250379 Anti-parasitic agent 3 2366983-10-8

Anti-parasitic agent 3 is an anti-parasitic agent which active against drug resistant parasites.

YN371048 NPD-1335 2376326-31-5

NPD1335 is aTrypanosoma brucei phosphodiesterase B1(TbrPDEB1) inhibitor with submicromolar activities againstT. bruceiparasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAM...

YN250389 ZL0580 2377151-10-3

ZL0580, a structurally close analog of ZL0590, induces epigenetic suppression ofHIVvia selectively binding to BD1 domain ofBRD4. ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongati...

YN250558 Neuraminidase-IN-1 2379438-80-7

Neuraminidase-IN-1 is aneuraminidaseinhibitor, with an IC50 of 0.21μM. Neuraminidase-IN-1 has excellent activity againstH1N1 influenza virus and good inhibitory effect on the A/WSN/33 H1N1 virus strains.

YN250418 SPR206 acetate 2408422-41-1

SPR206 acetate is a polymyxin analog with antibiotic activity againstGram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s...

YN250380 TCMDC-135051 2413716-15-9

TCMDC-135051 is a highly selective and potent protein kinasePfCLK3inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mos...

YN250448 JH-LPH-33 2414590-04-6

JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolaseLpxHinhibitor. JH-LPH-33 displays outst and ingantibioticactivity with a MIC value of 0.66 μg/mL.

YN250447 JH-LPH-28 2414592-36-0

JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolaseLpxHinhibitor. JH-LPH-28 displays outst and ingantibioticactivity with a MIC value of 0.83 μg/mL.

YN481363 EBOV/MARV-IN-1 2479465-67-1

EBOV/MARV-IN-1 is a potent inhibitor ofEbola virus (EBOV) and Marburg virus (MARV), with broad-spectrum activity (EC50=0.31, and 0.82 µM, respectively) and low cytotoxicity (SI>100) in HeLa cells.