YN250586 Luliconazole 187164-19-8

Luliconazole is a broad-spectrum antifungal drug.

YN371387 Oseltamivir acid 187227-45-8

Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor ofinfluenza virus neuraminidase (IC50=2nM)with activity against both influenza A and B viruse...

YN250163 Pretomanid 187235-37-6

PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.

YN250716 Abacavir sulfate 188062-50-2

Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.

YN250059 MBP146-78 188343-77-3

MBP146-78 is a potent and selective inhibitor of cyclic GMP(cGMP)-dependent protein kinases/Protein Kinase G (PKG) and displays cytostatic activity against Toxoplasma gondii.

YN251836 Temporin A 188713-69-1

Temporin A is a short alpha-helicalantimicrobialpeptide isolated from the skin of the frogRana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membr...

YN251869 Temporin L 188713-81-7

Temporin L is a potent antimicrobial peptide and is active againstGram-negative bacteria and yeast strains. Temporin L also has antiendotoxin properties.

YN250600 Delafloxacin 189279-58-1

Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistantStaphylococcus aureus,Streptococcus pneumoniae, and Klebsiella pn...

YN250065 WQ 2743 189280-13-5

WQ 2743 is a potent antimicrobial agent.

YN250628 Epothilone D 189453-10-9

Epothilone D (KOS 862) is a potentmicrotubulestabilizer.

YN250858 Telithromycin 191114-48-4

Telithromycin(HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Telithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the...

YN321234 CS-003 Free base 191672-52-3

CS-003 Free base (CS-003), a triple tachykinin receptor antagonist, shows high affinities for human (Neurokinin) NK1, NK2 and NK3 receptors with Ki values of 2.3nM, 0.54nM and 0.74nM, respectively. CS-003 Free base (C...

YN251811 TAT 191936-91-1

TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologo...

YN250057 Iclaprim 192314-93-5

Iclaprim is a new selective bacterialDihydrofolateinhibitor, which can inhibit the growth ofS. aureus(MRSA) with anMIC90of 0.06 μg/mL.

YN251366 Oritavancin diphosphate 192564-14-0

Oritavancin diphosphate (LY333328 diphosphate) is a semisynthetic glycopeptide antibiotic being developed for the treatment of serious Gram-positive bacterial infections.Oritavancin is a lipoglycopeptide.Oritavancin has completed clin...

YN372211 Lopinavir 192725-17-0

Lopinavir is a potent HIV protease inhibitor with Ki of 1.3 pM in a cell-free assay.

YN371766 Lopinavir Metabolite M-1 192725-39-6

Lopinavir Metabolite M-1, an active metabolite of Lopinavir, inhibitsHIV proteasewith a Ki of 0.7 pM. Lopinavir Metabolite M-1 has antiviral activities in vitro.

YN372260 Lonafarnib 193275-84-2

Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.

YN250040 Fosfluconazole 194798-83-9

Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.

YN250729 Garenoxacin 194804-75-6

Garenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes.