YN371001 (R)-Citronellol 1117-61-9

(R)-Citronellol (D-Citronellol) is an alcoholic monoterpene found in geranium essential oil. (R)-Citronellol inhibits degranulation of mast cells and does not affect caffeine bitterness perception. (R)-Citronellol can be used in d...

YN270452 Tetramethylpyrazine 1124-11-4

Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.

YN251896 3,5-Dimethoxybenzoic acid 1132-21-4

3,5-Dimethoxybenzoic acid, isolated fromMelia azedarach L.leaves with antifungal activity, is an intermediate in organic synthesis.

YN483582 Isolongifolene 1135-66-6

Isolongifolene ((-)-Isolongifolene) is a tricyclic sesquiterpene isolated fromMurraya koenigii. Isolongifolene attenuates Rotenone-induced oxidative stress, mitochondrial dysfunction and apoptosis through the regulation of P13K/AK...

YN373325 Caryophyllene oxide 1139-30-6

Caryophyllene oxide, an oxygenated terpenoid existed in many plant essential oil, is well known as preservative in food, drugs and cosmetics with anti-inflammatory, anti-carcinogenic and skin penetration enhancing properties.

YN350117 Urolithin B 1139-83-9

Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα. Urolithin B suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphoryla...

YN481856 Dithranol 1143-38-0

Dithranol is one of the most important local therapeutic agents against the common skin disease, psoriasis.

YN483215 Columbianetin 1147-29-1

Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity.

YN360111 EIPA 1154-25-2

EIPA (L593754) is aTRPP3 channelinhibitor with an IC50 of 10.5μM. EIPA also inhibitsNa+/H+-exchanger(NHE) and macropinocytosis .

YN480986 Luteolinidin chloride 1154-78-5

Luteolinidin is a natural deoxyanthocyanidin, isolated from mosses and ferns. Luteolinidin is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothe...

YN360208 Phenamil methanesulfonate 1161-94-0

Phenamil methanesulfonate, an analog of Amiloride (HY-B0285), is a more potent and less reversibleepithelial sodium channel (ENaC)blocker with an IC50 of 400nM. Phenamil methanesulfonate is also a competive inhibitor ofTRPP...

YN321267 Clemizole hydrochloride 1163-36-6

Clemizole hydrochloride is anH1 histamine receptorantagonist, is found to substantially inhibitHCVreplication. TheIC50 of Clemizole for RNA binding byNS4Bis 24±1nM, whereas itsEC50 for viral replication is 8 µM.

YN483204 Scutellarein tetramethyl ethe... 1168-42-9

Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive component of Siam weed extract. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) exhibits anti-inflammatory activity through NF-κB pathway. S...

YN250591 Dexamethasone acetate 1177-87-3

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

YN371176 Taurodeoxycholate sodium salt 1180-95-6

Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses .

YN482431 1,4-Dicaffeoylquinic acid 1182-34-9

1,4-Dicaffeoylquinic acid (1,4-DCQA) is a phenylpropanoid fromXanthii fructus, inhibits LPS-stimulated TNF-α production.

YN330147 Trimethylamine N-oxide 1184-78-7

Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating theROS/NLRP3 inflammasome. Trimethylamine...

YN330362 Lipoic acid 1200-22-2

R(+)-α-lipoic acid, a physiological form of thioctic acid, is a strong antioxidant that relieves diabetic neuropathic symptoms. It shows superior antioxidative effects to its racemate.

YN330263 7,8-Dihydroneopterin 1218-98-0

7,8-Dihydroneopterin, an inflammation marker, induces cellularapoptosisin astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseas...

YN483384 Retusin 1245-15-4

Retusin (Quercetin-3,3',4',7-tetramethylether), a natural compound isolated from the leaves ofTalinum triangulare, possesses antiviral and anti-inflammatory activities.