YN321530 Hydroxyzine dihydrochloride 2192-20-3

Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [3H]pyrilamine/[3H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.

YN321757 7,4'-Dihydroxyflavone 2196-14-7

7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated fromGlycyrrhiza uralensis, theeotaxin/CCL11inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effec...

YN321653 Hydrocortisone hemisuccinate 2203-97-6

Hydrocortisone hemisuccinate (A-hydrocort, Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid with anti-inflammatory properties, is an inhibitor of proinflammatory cytokine with IC50 of 6.7 μM and 21.4 μM for <...

YN321763 Cyclobuxine D 2241-90-9

Cyclobuxine D is a steroidal alkaloid extracted fromBuxus microphylla. Cyclobuxine D has a significant bradycardic effect in the rat heart and an inhibitory action onacetylcholine and Ba++−induced contraction of the longitudinal m...

YN373194 Robustine 2255-50-7

Robustine, a furoquinoline alkaloid, fromDictamnus albus, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro.

YN483350 Diacetoxyscirpenol 2270-40-8

Diacetoxyscirpenol (DAS) is a trichothecene mycotoxin, a secondary metabolite product of fungi. Diacetoxyscirpenol (DAS) consumption induces haematological disorders (neutropenia, aplastic anemia) in human and animals.

YN481951 Iotalamic acid 2276-90-6

Lotalamic acid (Iothalamic acid) is a molecule used as a contrast medium.

YN350275 Ferulic acid methyl ester 2309-07-1

Methyl ferulate is a lipophilic derivative of ferulic acid, which is a hydroxycinnamic acid that is abundant in plants. It shows the strongest antioxidant activity and can protect against inflammation and cancer.

YN481954 6α-Methylprednisolone 21-hem... 2375-03-3

Methylprednisolone sodium succinate is a corticosteroid medication that reduces inflammation.

YN270551 Liensinine perchlorate 2385-63-9

Liensinine Perchlorate is a constituent ofNelumbo nucifera Gaertn, with ani-hypertension and anti-cancer activities. Liensinine Perchlorate induces colorectal cancer (CRC) cellapoptosis.

YN321683 Dexamethasone phosphate disod... 2392-39-4

Dexamethasone phosphate disodium (DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex) is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.

YN321604 Dexchlorpheniramine maleate 2438-32-6

Dexchlorpheniramine maleate is an antihistamine, with anticholinergic properties, used to treat allergic conditions.

YN290504 Bufexamac 2438-72-4

Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.

YN360184 Kynurenic acid sodium 2439-02-3

Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targetingNMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist ofGPR35/CXCR8.

YN483182 7,8-Dimethoxycoumarin 2445-80-9

7,8-Dimethoxycoumarin (Daphnetin dimethyl ether) is a coumarin fromArtemisia caruifolia.

YN330515 Isochlorogenic acid A 2450-53-5

Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with antioxidant and anti-inflammatory activities .

YN481956 Terpin hydrate 2451-01-6

Terpin hydrate is an expectorant, commonly used to loosen mucus in patients presenting with acute or chronic bronchitis, and related conditions.

YN270622 Triglycidyl isocyanurate 2451-62-9

Triglycidyl Isocyanurate, also known as Teroxirone, is a triazene triepoxide with antineoplastic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl Isocyanurate alkylates and c...

YN372564 Oxypurinol 2465-59-0

Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor ofxanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout.

YN410120 Tenuigenin 2469-34-3

Tenuigenin is a major active component isolated from the root of the Chinese herbPolygala tenuifolia. Tenuigenin protects against S.aureus-induced pneumonia by inhibitingNF-κBactivation. Tenuigenin has anti-inflammatory effect.