YN251778 Pinocembrin chalcone 4197-97-1

Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is anantibacterialcompound fromHelichrysum Trilineatum. Pinocembrin chalcone can prevent gastric ulcers in rats.

YN321538 (S)-(-)-Propranolol hydrochl... 4199-10-4

(S)-(-)-Propranolol hydrochloride, the active enantiomer of propranolol, is a β-Adrenoceptor (β-Adrenergic Receptor) antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively.

YN321963 ACTH (11-24) 4237-93-8

ACTH (11-24) is a fragment of adrenocorticotrophin, acts as an antagonist ofadrenocorticotropic hormone (ACTH) receptor, and induces cortisol release.

YN330578 Isoorientin 4261-42-1

Isoorientin is a potent inhibitor of COX-2 with an IC50 value of 39 μM.

YN482953 Tilianin 4291-60-5

Tilianin is a flavonoid glycoside ofDragocephalum moldavicum L..

YN250501 Cletoquine 4298-15-1

Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine deriv...

YN480897 Alimemazine hemitartrate 4330-99-8

A phenothiazine derivative that is used as an antipruritic.

YN251507 Maslinic acid 4373-41-5

Maslinic acid is a DNA polymerase B inhibitor.

YN482754 Perakine 4382-56-3

Perakine is an indole alkaloid isolated fromAlstonia yunnanensis. Anti-inflammatory activities.

YN360792 Niflumic acid 4394-00-7

Niflumic acid is an inhibitor of cyclooxygenase-2 used for joint and muscular pain.

YN321664 Beclometasone 4419-39-0

Beclometasone (Beclomethasone) is a prototypeglucocorticoid receptoragonist.

YN482668 Tabersonine 4429-63-4

Tabersonineis a terpene indole alkaloid found in the medicinal plant Catharanthus roseus.

YN360325 Aurintricarboxylic acid 4431-00-9

Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitiveP2X1Rs and P2X3Rs, with IC50s of 8.6nM and 72.9nM for rP2X1R and rP2X3R, respectively. Aurin...

YN280129 Ligustilide 4431-01-0

Ligustilide may have the neuroprotective potential of Ligustilide in cerebral ischemic damage via antioxidant and anti-apoptotic properties. Ligustilide and senkyunolide A have vasorelaxation activities in contractions to various contra...

YN440426 Warangalone 4449-55-2

Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite3D7(chloroquine sensitive) and K1(chloroquine resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also...

YN340133 ZM 449829 4452-06-6

ZM 449829 is a potent, selective and ATP competitive inhibitor ofJAK3, with apIC50 of 6.8. ZM 449829 will be useful pharmacological tools for the investigation of theJAK3.

YN330017 Asaraldehyde 4460-86-0

Asaraldehyde is a natural COX-2 inhibitor, exhibiting 17-fold selectivity over COX-1.

YN410055 Sulforaphane 4478-93-7

Sulforaphane is a naturally occurring isothiocyanate derived from the consumption of cruciferous vegetables, such as broccoli, cabbage, and kale. It is an inducer of Nrf2.

YN482063 Choline theophyllinate 4499-40-5

N/A

YN410144 Valencene 4630-07-3

Valencene is a sesquiterpene isolated fromCyperus rotundus, possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammato...