YN482783 Phellopterin 2543-94-4

Phellopterin is a natural product isolated fromP. trifoliata. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to ...

YN481760 Diflorasone 2557-49-5

Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties.

YN290047 N6,N6-Dimethyladenosine 2620-62-4

N6,N6-Dimethyladenosine is a modified ribonucleoside previously found in rRNA, and also exhibits in mycobacterium bovis Bacille Calmette-Guérin tRNA.

YN481719 4-Acetamidophenyl acetate 2623-33-8

4-Acetamidophenyl acetate is an impurity of Acetaminophen (paracetamol). Acetaminophen, an analgesic drug, is a selective COX-2 inhibitor (IC50=25.8μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

YN480378 6-Aminochrysene 2642-98-0

6-Aminochrysene (6-Aminochrysene) is an aromatic amine used as a chemotherapeutic agent in the treatment of splenomegaly, myeloid leukemia, and breast cancer.

YN373391 4'-Hydroxychalcone 2657-25-2

4'-Hydroxychalcone, found in herbs and spices and tea, is a member of the class of compounds known as retrochalcones. It has diverse biological activities, inhibiting TNFα-induced NF-κB pathway activation in a dose-dependent manne...

YN481960 Medrysone 2668-66-8

Medrysone is a corticosteroid, in ophthalmology for the treatment of eye inflammations.

YN330564 Dehydrodiisoeugenol 2680-81-1

Dehydrodiisoeugenol has anti-inflammatory activity. (1) Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2) Dehydrodiisoeugenol inhibited LPS-stimulated phosphoryl...

YN483691 Tetra-N-acetylchitotetraose 2706-65-2

Tetra-N-acetylchitotetraose elicits plant defense systems. Tetra-N-acetylchitotetraose is a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia. Tetra-N-acetylchitotetraose is also a substrate for theRhizobium...

YN480861 (R,S)-Anatabine 2743-90-0

(R,S)-Anatabine is a a minor tobacco alkaloid found in theSolanaceaefamily of plants that can be used as a specific marker for the detection of tobacco use.

YN320251 Monomethyl fumarate 2756-87-8

Monomethyl Fumarate (MMF, Monomethylfumarate, Fumaric acid monomethyl ester, Methyl hydrogen fumarate), the active metabolite of the psoriasis drug Fumaderm, is a potent GPR109A agonist. Monomethyl Fumarate prevents major dys...

YN251570 Bellidifolin 2798-25-6

Bellidifolin is a xanthone isolated from the stems ofSwertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities . Bellidifolin also acts as aviral protein R (Vpr)inhibitor.

YN330332 Tyrphostin A1 2826-26-8

Tyrphostin A1(AG9) inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells.

YN483075 Heraclenin 2880-49-1

Heraclenin, a natural furanocoumarin, isolated from the root parts of the plantPrangos pabularia. Heraclenin significantly inhibits T cell receptor-mediated proliferation in human primary T cells in a concentration-dependent manner by...

YN481964 Prednisolone hemisuccinate 2920-86-7

Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.

YN321687 Methylprednisolone succinate 2921-57-5

Methylprednisolone sodium succinate is a glucocorticoid used to treat a variety health issues including severe allergic reactions, asthma, autoimmune diseases, blood disorders, gastrointestinal diseases and endocrine disorders.

YN330069 L-Kynurenine 2922-83-0

L-Kynurenine is a metabolite of the amino acid L-tryptophan used in the production of niacin. It is also a central compound of the tryptophan metabolism pathway.

YN251617 Sakuranetin 2957-21-3

Sakuranetin is a rice flavonoid phytoalexin, shows strong antifungal activity. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury.

YN482762 1,3,5,8-Tetrahydroxyxanthone 2980-32-7

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted fromGentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity.

YN482637 Toxicarol isoflavone 3044-60-8

Toxicarol isoflavone is an isoflavone extracted fromMillettia br and isiana.