YN321752 Agnuside 11027-63-7

Agnuside is a compound isolated fromVitex negundo, down-regulates pro-inflammatory mediatorsPGE2 and LTB4, and reduces the expression of cytokines, with anti-arthritic activity.

YN370807 Enocyanin 11029-12-2

Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity.

YN250867 Tunicamycin 11089-65-9

Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibitsN-linked glycosylation and blocksGlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) ...

YN483414 Cauloside D 12672-45-6

Cauloside D is a triterpene glycoside isolated fromCaulophyllum robustumMax. Cauloside D exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines.

YN340263 Nitidine chloride 13063-04-2

Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identifies efficac...

YN321344 Decloxizine dihydrochloride 13073-96-6

Decloxizine dihydrochloride(UCB-1402; NSC289116) is a histamine 1 receptor antagonist.

YN330131 D-α-Hydroxyglutaric acid 13095-47-1

D-α-Hydroxyglutaric acid ((R)-2-Hydroxypentanedioic acid) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid is a weak competitive antagonist ofα-ketoglutarate...

YN480348 5-Acetylsalicylic acid 13110-96-8

5-Acetylsalicylic acid, also known as Mesalazine or Mesalamine, is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease.

YN270494 Periplocin 13137-64-9

Periplocin has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. Periplocin is used for treatment of rheumatoid arthritis, reinforcement of bones a...

YN373139 Solanesol 13190-97-1

Solanesol (Nonaisoprenol, Betulanonaprenol) is a long-chain polyisoprenoid alcohol compound with inhibitory activities toward FAK. It mainly accumulates in solanaceous crops, including tobacco, tomato, potato, eggplant, and pe...

YN483126 Dihydrocucurbitacin B 13201-14-4

Dihydrocucurbitacin B, a triterpene isolated fromCayaponia tayuyaroots, inhibits nuclear factor of activated T cells (NFAT), induces cell cycle arrested in the G0 phase, and inhibits delayed type hypersensitivity.

YN320395 Vamorolone 13209-41-1

Vamorolone (VBP15) is a first-in-class, orally activedissociative steroidal anti-inflammatorydrug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone shows potentNF-κBinhibition and ...

YN483320 Tryptanthrin 13220-57-0

Tryptanthrin is a potent and orally active cellularLeukotriene (LT) biosynthesisinhibitor. Tryptanthrin inhibits LT formation in human whole blood (IC50= 10 µM) and reduces LTB4 levels in the rat pleurisy model.

YN482367 Neohesperidin 13241-33-3

Neohesperidin, a flavanone glycoside found in citrus fruits, is an antioxidant agent.

YN321592 Fenoterol 13392-18-2

Fenoterol is a β2 adrenoreceptor agonist with bronchodilator activity.

YN270506 Aristolactam I 13395-02-3

Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potenc...

YN270385 DCVC 13419-46-0

DCVC (S-[(1E)-1,2-dichloroethenyl]--L-cysteine) is a bioactive metabolite of trichloroethylene (TCE). DCVC inhibits pathogen-stimulated pro-inflammatory cytokines IL-1β, IL-8, and TNF-αrelease from tissue cultures.

YN483340 3-Carene 13466-78-9

3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates...

YN373162 Linderane 13476-25-0

Linderane was characterized as a mechanism-based inactivator of CYP2C9.

YN321595 Hydrocortisone 17-butyrate 13609-67-1

Hydrocortisone butyrate is a potent topical corticosteroid that can be used to treat a range of inflammatory skin conditions.