YN250493 Eleutheroside B1 16845-16-2

Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-humaninfluenza virusefficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. E...

YN372853 Bucladesine sodium 16980-89-5

Dibutyryl-cAMP (Bucladesine) is a cell-permeable PKA activator by mimicing the action of endogenous cAMP.

YN483908 Secretin, porcine 17034-34-3

Secretin, porcine (Porcine secretin acetate) is a 27-amino acid peptide, acting on pancreatic acinar cells and ductal epithelial cells stimulating the production of bicarbonate rich fluid.

YN360959 Isosinensetin 17290-70-9

Isosinensetin, a polymethoxylated flavone extracted from pericarpium citri reticulatae viride, exhibits inhibition onP-glycoprotein (P-gp)in MDR1-MDCKII cells.

YN483946 N-Formyl-Met-Ala-Ser 17351-32-5

N-Formyl-Met-Ala-Ser is a peptide, binds toformyl peptide receptorson neutrophils.

YN330081 Tetrahydrobiopterin 17528-72-2

Tetrahydrobiopterin is acofactorof thearomatic amino acid hydroxylases enzymes and also acts as an essentialcofactorfor allnitric oxide synthase(NOS) isoforms.

YN410127 Homoplantaginin 17680-84-1

Homoplantaginin has a protective and therapeutic effect on hepatocyte injury, which might be associated with its antioxidant properties. Homoplantaginin ameliorates endothelial insulin resistance by inhibiting inflammation and modulating ...

YN480736 Clonixin 17737-65-4

Clonixin is a nonsteroidal anti-inflammatory drug with analgesic, antipyretic, and platelet-inhibitory actions.

YN280125 Peiminine 18059-10-4

Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity. Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung i...

YN330587 Jaceosidin 18085-97-7

Jaceosidin is a flavonoid isolated fromArtemisia vestita, induces apoptosis in cancer cells, activatesBax and down-regulates Mcl-1 and c-FLIP expression. Jaceosidin exhibits anti-cancer , anti-inflammatory activities, decreases ...

YN482790 Nigakinone 18110-86-6

Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu.

YN251718 Netropsin dihydrochloride 18133-22-7

Netropsin (dihydrochloride) is a small-molecule MGB (minor-groove binder), inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nu...

YN360223 BL-1249 18200-13-0

BL-1249 is anonsteroidal anti-inflammatory drug (NSAID) and apotassium channelactivator. BL-1249 potently activatesK2P2.1 (TREK-1) and K2P10.1 (TREK-2)withEC50values of 5.5μM and 8.0μM, respectively. BL-1249 ...

YN310061 KG-501 18228-17-6

KG-501 is a cAMP response element-binding protein (CREB) inhibitor that disrupts CREB-dependent transcription (Ki = 10 μM) and CREB:CBP interaction (Ki = 50 μM). It also disrupts phospho (Ser-133) CREB...

YN482909 Baldrinal 18234-46-3

Baldrinal is derived from the extracts of valerian rhizomes and roots, inhibits autonomic activity, and has anti-inflammatory effects.

YN482876 Fabiatrin 18309-73-4

Fabiatrin is a natural product isolated fromPrzewalskia tangutica.

YN330562 Madecassic acid 18449-41-7

Madecassic acid, a natural triterpene first isolated from C. asiatica, has diverse anti-inflammatory and anti-diabetic effects, blocking NF-κB activation in macrophages and altering lipid metabolism in mice, at least in part through a...

YN483578 Bakkenolide B 18455-98-6

Bakkenolide B is isolated frompetasites japonicasleaves and has anti-allergic and anti-inflammatory effects. Bakkenolide B can be used for the study of asthma.

YN330635 Brevifolincarboxylic acid 18490-95-4

Brevifolincarboxylic acid is extracted fromPolygonum capitatum , has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is anα-glucosidaseinhibitor with an IC50 of 323.46μM.

YN481942 L-Cysteine methyl ester hydr... 18598-63-5

L-Cysteine methyl ester hydrochloride is an antitussive, and an expectorant agent, used to relieve breathing difficulties caused by mucus.