YN360991 Sinapine 18696-26-9

Sinapine is an alkaloid isolated from seeds of the cruciferous species with antioxidant, antitumor and radio-protective activities. Sinapine inhibits the proliferation of Caco-2 cells via downregulation of P-glycoprotein.

YN481735 Actarit 18699-02-0

Actarit is an orally active immunomodulator used in the treatment of rheumatoid arthritis.

YN380237 Corynoline 18797-79-0

Corynoline, isolated from the aerial parts of Corydalis incisa, has inhibitory effect on the acetylcholinesterase with reversible and noncompetitive. Corynoline exhibits the potent anti-inflammatory and/or immunosuppressive activity, ...

YN482546 Acetylcorynoline 18797-80-3

Acetylcorynoline is the major alkaloid component derived fromCorydalis bungeana, and has anti-inflammatory properties.

YN330535 Cardamonin 18956-16-6

Cardamonin, isolated from the fruits of Alpinia species, is a chalconoid with anti-inflammatory and anti-tumor activity. It has been shown to be a novel antagonist of hTRPA1 cation channel with IC50 of 454 nM while does not intera...

YN280145 Salvigenin 19103-54-9

Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties.

YN330547 Harpagoside 19210-12-9

A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells.

YN300019 Benproperine phosphate 19428-14-9

Benproperine phosphate is a cough suppressant.

YN373264 Curcumenol 19431-84-6

Curcumenol, a sesquiterpene isolated from Curcuma zedoaria, is known to possess a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB...

YN410051 BAY 11-7082 19542-67-7

BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. Also inhibiting components of the ubiquitin system.

YN373190 Stigmasterol glucoside 19716-26-8

Stigmasterol glucoside is a sterol isolated fromP. urinariawith high antioxidant and anti-inflammatory activities , act as an inhibitor of5α-reductasewith an IC50 of 27.2 µM.

YN370405 Methotrexate metabolite 19741-14-1

Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is afolic acidantagonist that is widely used as an immunosuppressant and chemotherapeutic agent.

YN481092 Oxothiazolidinecarboxylic aci... 19771-63-2

Oxothiazolidinecarboxylic acid, an antioxidant, is a prodrug of cysteine that is inert until metabolized to cysteine intracellulary, thus stimulating glutathione synthesis.

YN484367 Uridine triphosphate trisodiu... 19817-92-6

Uridine-5'-triphosphate (UTP) is a pyrimidine nucleoside triphosphate and a substrate for the synthesis of RNA during transcription.

YN482393 Bavachinin 19879-30-2

Bavachinin is a novel natural pan-PPAR agonist from the fruit of the traditional Chinese glucose-lowering herb malaytea scurfpea. It shows stronger activities with PPAR-γ than with PPAR-α and PPAR-β/δ (EC50?=?0.74 μ...

YN251727 Continentalic acid 19889-23-7

Continentalic acid fromAralia continentalishas minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL againstS. aureus, including the Methicillin susceptibleStaphylococcus aureus(MSSA) and Methicillin-resistan...

YN482764 Kaempferol 3-O-sophoroside 19895-95-5

Kaempferol 3-O-sophoroside, a derivative of Kaempferol, is isolated from the leaves of cultivated mountain ginseng (Panax ginseng) with anti-inflammatory effects.

YN373182 Dihydromethysticin 19902-91-1

Dihydromethysticin is one of the six major kavalactones found in the kava plant; has marked activity on the induction of CYP3A23.

YN340149 Stattic 19983-44-9

Stattic, the first nonpeptidic small molecule, potently inhibits STAT3 activation and nuclear translocation with IC50 of 5.1 μM in cell-free assays, highly selectivity over STAT1.

YN1710002 N6-(2-Phenylethyl)adenosine 20125-39-7

N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine), an adenosine derivative, is a potentadenosine receptors (AR)agonist with Ki values of 11.8nM, 30.1nM, 0.63nM for rat A1AR, human A1AR and hA3AR, respectively.