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Inflammation/Immunology

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN320273 AH 6809 33458-93-4

    AH 6809 is an antagonist ofEP and DP receptor, with a Ki of 1217, 1150, 1597, and 1415nM for the clonedhuman EP1,EP2,EP3-III, and DP receptorrespectively, and with a Ki of 350nM formouse EP2receptor .

  • YN482932 4'-Methoxyresveratrol 33626-08-3

    4-Methoxyresveratrol is a stibenoid found in the Chinese herb Gnetum cleistostachyum.

  • YN270536 Britannin 33627-28-0

    Britannin, isolated fromInula aucheriana, is a sesquiterpene lactone. Britannin inducesapoptosis and autophagyby activating AMPK regulated by ROS in liver cancer cells. Britannin has anti-proliferative and anti-inflammatory act...

  • YN330592 Inulicin 33627-41-7

    Inulicin (1-O-Acetylbritannilactone) is an active compound isolated fromInula Britannica L. Inulicin (1-O-Acetylbritannilactone) inhibits VEGF-mediated activation ofSrc and FAK. Inulicin (1-O-Acetylbritannilactone) inhib...

  • YN360987 Hypophyllanthin 33676-00-5

    Hypophyllanthin is a major lignan inPhyllanthus spp, with strong anti-inflammatory activity. Hypophyllanthin directly inhibitsP-glycoprotein (P-gp)activity and did not interfere with multidrug resistance protein 2 (MRP2) activity.

  • YN251552 (R)-Fangchinoline 33889-68-8

    Fangchinoline, a bisbenzylisoquinoline alkaloid, is a novel HIV-1 inhibitor with pain-relieving, blood pressure-depressing, and antibiotic activities.

  • YN481592 Oxaceprol 33996-33-7

    Oxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis.

  • YN251225 Auranofin 34031-32-8

    Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2μM. Auranofin exhibits antiviral activity againstSARS-CoV21, with a CC50of 4.2 μM for monkey kidney Vero E6 cells.

  • YN483400 Glycyrrhetic acid 3-O-β-D-... 34096-83-8

    Glycyrrhetic acid 3-O-β-D-glucuronide, isolated fromglycyrrhiza, is an important derivative of glycyrrhizin (GL) with an anti -allergic activity. Glycyrrhetic acid 3-O-β-D-glucuronide (GAMG) shows that β‐glucuronidases (β‐...

  • YN371241 Tripterin 34157-83-0

    Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.

  • YN330610 Pterosin B 34175-96-7

    Pterosin B, a indanone found in bracken fern (Pteridium aquilinum), is an inhibitor ofsalt-inducible kinase 3 (Sik3)signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.

  • YN482409 Echinatin 34221-41-5

    Echinatin disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-A...

  • YN310357 Chelerythrine 34316-15-9

    Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependentPKCantagonist, with an IC50 of 0.7μM. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity. Chelerythrine inhi...

  • YN374137 ATP disodium salt hydrate 34369-07-8

    Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.

  • YN321675 Levalbuterol 34391-04-3

    Levalbuterol ((R)-Albuterol; (R)-Salbutamol) is a short-actingβ2-adrenergic receptoragonist and the active (R)-enantiomer of Salbutamol. Levalbuterol is a more potent bronchodilator than Salbutamol and has the potential for th...

  • YN483709 N-Demethyl-α-obscurine 34399-44-5

    N-Demethyl-α-obscurine, a lycodine-typeLycopodiumalkaloid, is isolated fromLycopodii Herba.

  • YN481199 4-Hydroxyacetophenone oxime 34523-34-7

    4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic drug.

  • YN330470 Isoxicam 34552-84-6

    Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis. Isoxicam is a nonselective inhibitor ofCOX-1 and COX-2.

  • YN321397 Ketotifen fumarate 34580-14-8

    Ketotifen Fumarate is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.

  • YN330422 Fenoprofen Calcium 34597-40-5

    Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.

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