YN410141 Kamebakaurin 73981-34-7

Kamebakaurin is a natural compound isolated fromIsodon japonicus. Kamebakaurin is a potent inhibitor ofNF-κBactivation by directly targeting DNA-binding activity of p50.

YN330446 Ketorolac 74103-06-3

Ketorolac (Ketorolac tromethamine) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.

YN330403 Ketorolac tromethamine salt 74103-07-4

Ketorolac is a synthetic pyrrolizine carboxylic acid derivative with anti-inflammatory, analgesic and antipyretic properties. It is a non-selective COX inhibitor with IC50s of 20 nM for both COX-1 and COX-2.

YN480147 Losmiprofen 74168-08-4

Losmiprofen is a nonsteroidal antiinflammatory agent.

YN320294 Dazoxiben 74226-22-5

Dazoxiben hydrochloride (HCl) is a potent, selevtive and orally active inhibitor of thromboxane (TX) synthase. Dazoxiben inhibits TXB2 production in clotting human whole blood with IC50 of 0.3 μM and causes parall...

YN330281 Indomethacin sodium hydrate 74252-25-8

Indomethacin sodium hydrate (Indometacin sodium hydrate) is a potent, blood-brain permeable and nonselective inhibitor ofCOX1 and COX2, with IC50s of 18nM and 26nM for human COX-1 and COX-2, respectively, in CHO c...

YN370426 C16-PAF 74389-68-7

C16-PAF (PAF (C16)), a phospholipid mediator, is a platelet-activating factor and lig and for PAF G-protein-coupled receptor (PAFR). C16-PAF exhibits anti-apoptotic effect and inhibits caspase-dependent death by act...

YN330455 Limaprost 74397-12-9

Limaprost (OP1206) is aPGE1analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost can be used for pain relief, has antianginal effects, and has potent...

YN482686 Liquiritin apioside 74639-14-8

Liquiritin apioside, a main flavonoid component of licorice, possesses antitussive effects.

YN483576 Apigenin-7-diglucuronide 74696-01-8

Apigenin-7-diglucuronide is a flavonoid glycoside and is present in an assortment of medicinal plants with anti-inflammatory or ant-oxidant activities. Apigenin-7-diglucuronide protects retinas against bright light-induced photoreceptor...

YN330450 Zaltoprofen 74711-43-6

Zaltoprofen is an inhibitor of COX-1 and COX-2 for treatment of arthritis.

YN482918 Methylophiopogonone A 74805-90-6

Methylophiopogonone A, a homoisoflavonoid isolated from the tuberous roots ofOphiopogon japonicas, shows anti-inflammatory activity.

YN482916 Methylophiopogonanone A 74805-92-8

Methylophiopogonanone A, a major homoisoflavonoid inOphiopogon japonicas, has both anti-oxidative and anti-inflammatory properties.

YN484171 Temarotene 75078-91-0

Temarotene is an orally administered, particular arotinoid.

YN330041 Nosantine racemate 75166-67-5

Nosantine racemate is the racemate of Nosantine. Nosantine is an inducer ofIL-2or enhancer ofIL-2induction by phytohemagglutinin (PHA).

YN310337 Ingenol Mebutate 75567-37-2

Ingenol Mebutate is an active ingredient inEuphorbia peplus, acts as a potentPKCmodulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has ...

YN481649 Fenclozine 75626-98-1

Fenclozine is a non-steroidal antiinflammatory drug extracted from patent WO 2012112690 A2.

YN484207 Antiulcer Agent 1 76001-09-7

Antiulcer Agent 1 is a 2-(3,4-dimethoxyphenyl)ethylamine derivative for oral administration at an exploratory stage of new drug development.

YN322036 KP136 76239-32-2

KP136 (AL136) is an orally effective antiallergic agent. TheIC50is 76.1 μg/mL forhistamine release and 63 ug/mL fordegranulation.

YN482523 Kalii Dehydrographolidi Suc... 76958-99-1

Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostim...