YN321384 Melatonin D4 66521-38-8

Melatonin D4 is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gl and that can activates melatonin receptor. Antioxidative and anti-inflammatory properties . Melatonin is a selective ATF-6 inhibitor and...

YN484066 {Boc}-Phe-Leu-Phe-Leu-Ph... 66556-73-8

{Boc}-Phe-Leu-Phe-Leu-Phe ({Boc}-FLFLF) is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor.

YN320969 Forskolin 66575-29-9

Forskolin is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology.

YN330447 (S)-Ketorolac 66635-92-5

(S)-Ketorolac is a nonsteroidal anti-inflammatory agent. (S)-ketorolac exhibits potentCOX1 and COX2enzyme inhibition.

YN330623 N-trans-Feruloyltyramine 66648-43-9

N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid fromPiper nigru, is an inhibitor ofCOX1 and COX2, with potential antioxidant properties. N-trans-Feruloyltyramine possesses anti-inflammatory activity.

YN372276 E-64 66701-25-5

E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM.

YN270595 D-Trimannuronic acid 66754-13-0

D-Trimannuronic acid, an alginate oligomer is extracted from seaweed. D-Trimannuronic acid can induce TNF‐α secretion by mouse macrophage cell lines. D-Trimannuronic acid can be used for the research of pain and vascular dement...

YN480184 Trehalose 6-behenate 66755-19-9

Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.

YN360135 Talniflumate 66898-62-2

Talniflumate is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma.

YN483943 N-Formyl-Met-Leu-Phe-Lys 67247-11-4

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist ofFPR1, with EC50s of 3.5nM, 6.7μM and 0.88μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.

YN480001 Ufenamate 67330-25-0

Ufenamate is an anthranilic acid derivative with anti-inflammatory activity.

YN321356 Alclometasone 67452-97-5

Alclometasone (7a-Chloro-16a-methyl prednisolone) is aglucocorticoid and inhibits the release of pro-inflammatory mediators from leukocytes. Alclometasone can be used to relieve corticosteroid-responsive dermatoses, including atopic de...

YN483048 Deapi-platycodin D3 67884-05-3

Deapi-platycodin D3 is a triterpenoid saponin from the roots ofPlatycodon gr and iflorum.

YN330618 Dehydroevodiamine 67909-49-3

Dehydroevodiamine, a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities.

YN482406 Aurantio-obtusin 67979-25-3

Inhibition of sEH (unknown origin) assessed as 6-methoxy-2-naphthaldehyde formation at 50 uM by fluorometry assay using 40 uM cyano-(6-methoxy-naphthalen-2-yl)-methyl ester as substrate

YN370989 CTPI-2 68003-38-3

CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with K_D of 3.5 μM. CTPI-2 is a unique regulator of glycolysis that limits the metabolic plasticity of cancer stem cells (CSCs).

YN330512 Ginsenoside Rb3 68406-26-8

Ginsenoside Rb3, extracted from the plant Panax ginseng, plays important roles in cardiovascular diseases, including myocardial ischemia-reperfusion (I/R) injury. Ginsenoside Rb3 (0.1-10 μM) is tested for inhibition of tumor necros...

YN484179 Apyramide 68483-33-0

Apyramide is ananti-inflammatory agent (NSAID) and behaves as a prodrug of indomethacin (HY-14397). Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1  and  COX2.

YN290114 N6-Etheno 2'-deoxyadenosine 68498-25-9

N6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissue...

YN440231 N-(p-Coumaroyl) Serotonin 68573-24-0

N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced onphosphorylation of PD...