Cot inhibitor-2
Cat. No. :YN350207
CAS No. :915363-56-3
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5mg
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Product Name: | Cot inhibitor-2 |
CAS NO.: | 915363-56-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 539.43 |
Molecular Formula: | C₂₆H₂₅Cl₂FN₈ |
SMILES: | N#CC1=C(C2=CC(NCC3=CN(N=N3)C4CCN(CC4)CC)=CC(Cl)=C2N=C1)NC5=CC=C(F)C(Cl)=C5 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Cot inhibitor-2 is a potent, selective and orally activecot (Tpl2/MAP3K8)inhibitor with an IC50 of 1.6nM. Cot inhibitor-2 inhibts TNF-α production in LPS-stimulated human whole blood with an IC50 of 0.3μM. |
IC50&Target: | |
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References: |
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