Cot inhibitor-1
Cat. No. :YN350206
CAS No. :915365-57-0
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order@ubiochem.com| Product Name: | Cot inhibitor-1 |
| CAS NO.: | 915365-57-0 |
| Chemical Name: | |
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| Molecular Weight: | 553.46 |
| Molecular Formula: | C₂₇H₂₇Cl₂FN₈ |
| SMILES: | N#CC1=C(C2=CC(NCC3=CN(CCN4CCCCCC4)N=N3)=CC(Cl)=C2N=C1)NC5=CC=C(F)C(Cl)=C5 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Cot inhibitor-1 (compound 28) is a selectivetumor progression loci-2 (Tpl2) kinaseinhibitor with an IC50 of 28nM. Cot inhibitor-1 shows an inhibition of TNF-alpha production in human whole blood with an IC50 of 5.7nM. |
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