Benzamil hydrochloride
Cat. No. :YN360877
CAS No. :161804-20-2
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order@ubiochem.com| Product Name: | Benzamil hydrochloride |
| CAS NO.: | 161804-20-2 |
| Chemical Name: | |
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| Molecular Weight: | 356.21 |
| Molecular Formula: | C₁₃H₁₅Cl₂N₇O |
| SMILES: | O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=CC=C2)=N.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+exchanger (NCX) inhibitor (IC50~100nM). Benzamil hydrochloride also is a non-selectiveDeg/epithelial sodium channels (ENaC)blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1μM . |
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