Benzamil
Cat. No. :YN360876
CAS No. :2898-76-2
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5mg
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Product Name: | Benzamil |
CAS NO.: | 2898-76-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 319.75 |
Molecular Formula: | C₁₃H₁₄ClN₇O |
SMILES: | O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=CC=C2)=N |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Benzamil (Benzylamiloride), an Amiloride analogue, is aNa+/Ca2+exchanger (NCX)inhibitor (IC50~100nM). Benzamil also is a non-selectiveDeg/epithelial sodium channels (ENaC)blocker, and can potentiate myogenic vasoconstriction. Benzamil inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1μM . |
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