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Neurological Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN370946 DL-Laudanosine 1699-51-0

    DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood–brain barrier and may cause excitement and seizure activity.

  • YN360795 Mepivacaine hydrochloride 1722-62-9

    Mepivacaine is a tertiary amine used as a local anesthetic.

  • YN360747 Riluzole 1744-22-5

    Riluzole is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anesthetic qualities.

  • YN360083 L-DABA 1758-80-1

    L-DABA (L-2,4-Diaminobutyric acid) is a weekGABAtransaminase inhibitor with an IC50 of larger than 500μM; exhibits antitumor activityin vivo and in vitro.

  • YN360706 (-)-Aspartic acid 1783-96-6

    (-)-Aspartic acid is an endogenousNMDAreceptor agonist.

  • YN360744 Prilocaine hydrochloride 1786-81-8

    Prilocaine hydrochloride is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions.

  • YN360881 Fluspirilene 1841-19-6

    Fluspirilene is a non-competitive antagonist ofL-type calcium channelswith an IC50 of 0.03μM. Fluspirileneis a long-acting injectable depot antipsychotic drug used for schizophrenia.

  • YN320411 Pregnenolone monosulfate sodi... 1852-38-6

    Pregnenolone monosulfate sodium salt (3β-Hydroxy-5-pregnen-20-one monosulfate sodium salt) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt acts a...

  • YN320075 Pipamperone 1893-33-0

    Pipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT2A receptor(pKi=8.2) and D4receptor(pKi=8.0) and a low-affinity antagonist of D2 receptor (pKi=6.7).

  • YN380150 Galanthamine hydrobromide 1953-04-4

    Galanthamine is an AChE inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase.

  • YN321271 Deschloroclozapine 1977-07-7

    Deschloroclozapine is a potent, high affinity, selective, metabolically stable agonist of muscarinic-basedDREADDs. Deschloroclozapine inhibites [3H]quinuclidinyl benzilate (QNB) binding to hM3Dq and hM4Di with Kiof 6.3 a...

  • YN321127 Loxapine 1977-10-2

    Loxapine (Adasuve), a typical neuroleptic, is a drug with D2/D3 receptor antagonist activity and a higher affinity for D3 than D2. Loxapine displays an extremely strong binding affinity for dopamine D4 and serotonin...

  • YN321265 Xanthotoxol 2009-24-7

    Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.

  • YN321649 Spiperone hydrochloride 2022-29-9

    Spiperone hydrochloride (Spiroperidol hydrochloride) is a selectivedopamine D2receptor(Kivalues of 0.06nM, 0.6nM, 0.08nM, ~350nM, ~3500nM forD2, D3, D4, D1 and D5receptors, respectively) and 5-HT2A/5-HT1Areceptor(Kis ...

  • YN320674 Pimozide 2062-78-4

    Pimozide is an antipsychotic drug of the diphenylbutylpiperidine class, which is a strong inhibitor of CYP2D6.

  • YN360822 Propofol 2078-54-8

    Propofol potently and directly activatesGABAAreceptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic.

  • YN321741 5-O-Demethylnobiletin 2174-59-6

    5-O-Demethylnobiletin has anti-inflammatory activity, it may act through a direct inhibition of 5-LOX, without affecting the expression of COX-

  • YN482952 (+)-Coclaurine 2196-60-3

    (+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity.

  • YN374161 6-Hydroxymelatonin 2208-41-5

    6-Hydroxymelatonin is a primary metabolic ofMelatonin, which is metabolized by cytochrome P450 (CYP) 1A2.

  • YN480099 Acetylcholine iodide 2260-50-6

    Acetylcholine iodide is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.

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