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Neurological Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN320703 Biperiden Hydrochloride 1235-82-1

    Biperiden Hydrochloride (KL 373 Hydrochloride) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker.

  • YN321677 Pregnenolone monosulfate 1247-64-9

    Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate acts as a signaling-specific inhibitor ofc...

  • YN380041 Pitofenone hydrochloride 1248-42-6

    Pitofenone hydrochloride, a spasmolytic compound, inhibits theacetylcholinesterase(AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45μM, respectively.

  • YN250319 Amylmetacresol 1300-94-3

    Amylmetacresol is an antiseptic used to treat infections of the mouth and throat.

  • YN310158 Nicotinamide riboside 1341-23-7

    Nicotinamide riboside, an orally active NAD+precursor, increases NAD+levels and activatesSIRT1 and SIRT3. Nicotinamide riboside is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against hi...

  • YN480805 DPN 1428-67-7

    DPN (Diarylpropionitrile) is a non-steroidalestrogen receptor β (ERβ)selective lig and , with an EC50 of 0.85nM. DPN has neuroprotective effects in a number of neurological diseases.

  • YN360902 Indole-2-carboxylic acid 1477-50-5

    Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation.

  • YN370285 3-Methoxytyramine hydrochlori... 1477-68-5

    3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activatetrace amine associated receptor 1(TAAR1).

  • YN360948 Menthol 1490-04-6

    Menthol is a natural analgesic compound. Menthol could cause a feeling of coolness due to stimulation of ‘cold’ receptors by inhibiting Ca++currents of neuronal membranes.

  • YN321440 Oxybutynin chloride 1508-65-2

    Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.

  • YN321450 Tropicamide 1508-75-4

    Tropicamide is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.

  • YN360871 Procyclidine hydrochloride 1508-76-5

    Procyclidine HCl blocks the effects of certain chemicals in the brain, and thus is used to treat Parkinson's disease or extrapyramidal side-effects caused by other medicines.

  • YN1730069 Haloperidol hydrochloride 1511-16-6

    Haloperidol hydrochloride is a potentdopamine D2 receptorantagonist, widely used as an antipsychotic.

  • YN320530 Metixene hydrochloride 1553-34-0

    Metixene hydrochloride is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to themuscarinic receptorin rat brain cortical tissue, with an IC50 of 55nM and aKdof 15nM.

  • YN360016 NS1652 1566-81-0

    NS1652 is a reversibleanion conductanceinhibitor, blockschloride channel, with an IC50 of 1.6μM in human and mouse red blood cells.

  • YN360419 GABAA receptor agent 1 1571-87-5

    GABAA receptor agent 1 is a high affinity lig and forGABAA receptor, with potent anticonvulsant activity.

  • YN1730108 Azaperone 1649-18-9

    Azaperone crosses the blood-brain barrier and binds to both DI and D2 receptors, being an antagonist of Dopamine receptors with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.

  • YN481848 Metaxalone 1665-48-1

    Metaxalone is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions.

  • YN380274 Epi-galantamine 1668-85-5

    Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibitsAChEwith an EC50 of 45.7μM .

  • YN360872 Tacrine hydrochloride 1684-40-8

    Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist.

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