Fabomotizole
Cat. No. :YN481409
CAS No. :173352-21-1
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order@ubiochem.com| Product Name: | Fabomotizole |
| CAS NO.: | 173352-21-1 |
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| Molecular Weight: | 307.41 |
| Molecular Formula: | C₁₅H₂₁N₃O₂S |
| SMILES: | CCOC1=CC=C2C(N=C(SCCN3CCOCC3)N2)=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Fabomotizole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA. |
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