DL-threo-2-methylisocitrate
Cat. No. :YN481547
CAS No. :71183-66-9
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order@ubiochem.com| Product Name: | DL-threo-2-methylisocitrate |
| CAS NO.: | 71183-66-9 |
| Chemical Name: | |
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| Molecular Weight: | 412.30 |
| Molecular Formula: | C₁₄H₂₀O₁₄ |
| SMILES: | O[C@@](C)(C(O)=O)[C@@]([H])(C(O)=O)CC(O)=O.O[C@](C)(C(O)=O)[C@]([H])(C(O)=O)CC(O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1(ICL1). The Km of purified recombinant ICL1 for threo-D(s)L(s)-isocitrate (ICA) was determined to be 188μM using Michaelis-Menten non-linear least squares fit, with a kcat of 5.24 s-1. The Km for DL-threo-2-methylisocitrate (MICA) was approximately fourfold higher at 718μM with a kcat of 1.25 s-1. |
| IC50&Target: | |
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