Axitinib
Cat. No. :YN440021
CAS No. :319460-85-0
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Product Name: | Axitinib |
CAS NO.: | 319460-85-0 |
Chemical Name: | |
Synonyms: | AG 013736 |
Molecular Weight: | 386.47 |
Molecular Formula: | C₂₂H₁₈N₄OS |
SMILES: | O=C(C1=C(SC2=CC3=C(C(/C=C/C4=CC=CC=N4)=NN3)C=C2)C=CC=C1)NC |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Axitinib is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively. |
IC50&Target: | |
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Clinical Trial: | |
Solvent & Solubility: | |
References: |
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