Cediranib
Cat. No. :YN440059
CAS No. :288383-20-0
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order@ubiochem.com| Product Name: | Cediranib |
| CAS NO.: | 288383-20-0 |
| Chemical Name: | |
| Synonyms: | NSC-732208 |
| Molecular Weight: | 450.51 |
| Molecular Formula: | C₂₅H₂₇FN₄O₃ |
| SMILES: | FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3 in HUVEC cells. Phase 3. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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