PF-4708671
Cat. No. :YN350169
CAS No. :1255517-76-0
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order@ubiochem.com| Product Name: | PF-4708671 |
| CAS NO.: | 1255517-76-0 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 390.41 |
| Molecular Formula: | C₁₉H₂₁F₃N₆ |
| SMILES: | FC(C1=CC=C2N=C(CN3CCN(C4=NC=NC=C4CC)CC3)NC2=C1)(F)F |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM in cell-free assays, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity for S6K1 than MSK1 and RSK1/2, respectively. First S6K1-specific inhibitor to be reported. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
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| Solvent & Solubility: | |
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