CKI-7
Cat. No. :YN350273
CAS No. :1177141-67-1
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5mg
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Product Name: | CKI-7 |
CAS NO.: | 1177141-67-1 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 358.67 |
Molecular Formula: | C₁₁H₁₄Cl₃N₃O₂S |
SMILES: | O=S(C1=CC=C(Cl)C2=C1C=NC=C2)(NCCN)=O.[H]Cl.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | CKI-7 is a potent and ATP-competitivecasein kinase 1 (CK1)inhibitor with an IC50 of 6μM and a Ki of 8.5μM. CKI-7 is a selectiveCdc7 kinaseinhibitor. CKI-7 also inhibitsSGK,ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 has a much weaker effect on casein kinase II and other protein kinases. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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