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CKI-7

Cat. No. :YN350273

  • CAS No. :1177141-67-1

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    • Products Infomation
    • Biological Activity
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    • Product Name:CKI-7
      CAS NO.:1177141-67-1
      Chemical Name:
      Synonyms:
      Molecular Weight:358.67
      Molecular Formula:C₁₁H₁₄Cl₃N₃O₂S
      SMILES:O=S(C1=CC=C(Cl)C2=C1C=NC=C2)(NCCN)=O.[H]Cl.[H]Cl
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:CKI-7 is a potent and ATP-competitivecasein kinase 1 (CK1)inhibitor with an IC50 of 6μM and a Ki of 8.5μM. CKI-7 is a selectiveCdc7 kinaseinhibitor. CKI-7 also inhibitsSGK,ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 has a much weaker effect on casein kinase II and other protein kinases.
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