Neratinib
Cat. No. :YN340231
CAS No. :698387-09-6
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5mg
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Product Name: | Neratinib |
CAS NO.: | 698387-09-6 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 557.04 |
Molecular Formula: | C₃₀H₂₉ClN₆O₃ |
SMILES: | ClC1=C(OCC2=NC=CC=C2)C=CC(NC3=C(C#N)C=NC4=CC(OCC)=C(NC(/C=C/CN(C)C)=O)C=C43)=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM in cell-free assays weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3. |
IC50&Target: | |
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References: |
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