CGP52411
Cat. No. :YN340043
CAS No. :145915-58-8
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order@ubiochem.com| Product Name: | CGP52411 |
| CAS NO.: | 145915-58-8 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 329.35 |
| Molecular Formula: | C₂₀H₁₅N₃O₂ |
| SMILES: | O=C1NC(C2=C1C=C(NC3=CC=CC=C3)C(NC4=CC=CC=C4)=C2)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CGP52411 (DAPH) is a high selective, potent, orally active and ATP-competitiveEGFRinhibitor with an IC50 of 0.3μM. CGP52411 blocks the toxic influx of Ca2+ions into neuronal cells, and dramatic inhibits and reverses the formation ofβ-amyloid (Aβ42)fibril aggregates associated with Alzheimer's disease. |
| IC50&Target: | |
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