Afatinib impurity 11
Cat. No. :YN340131
CAS No. :1402086-20-7
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order@ubiochem.com| Product Name: | Afatinib impurity 11 |
| CAS NO.: | 1402086-20-7 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 428.84 |
| Molecular Formula: | C₂₁H₁₈ClFN₄O₃ |
| SMILES: | O=C(NC1=C(C=C2C(C(NC3=CC(Cl)=C(C=C3)F)=NC=N2)=C1)O[C@H]4CCOC4)C=C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversibleEGFRfamily inhibitor with IC50s of 0.5nM, 0.4nM, 10nM and 14nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. |
| IC50&Target: | |
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