Dacomitinib
Cat. No. :YN340128
CAS No. :1110813-31-4
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order@ubiochem.com| Product Name: | Dacomitinib |
| CAS NO.: | 1110813-31-4 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 469.94 |
| Molecular Formula: | C₂₄H₂₅ClFN₅O₂ |
| SMILES: | O=C(/C=C/CN1CCCCC1)NC2=CC3=C(C=C2OC)N=CN=C3NC4=CC=C(C(Cl)=C4)F |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Dacomitinib (PF299804, PF299) is a potent, irreversible pan-ErbB inhibitor, mostly to EGFR with IC50 of 6 nM in a cell-free assay, effective against NSCLCs with EGFR or ERBB2 mutations (resistant to gefitinib) as well as those harboring the EGFR T790M mutation. Phase 2. |
| IC50&Target: | |
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| In Vivo: | |
| Clinical Trial: | |
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