AZ-5104
Cat. No. :YN340253
CAS No. :1421373-98-9
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5mg
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Product Name: | AZ-5104 |
CAS NO.: | 1421373-98-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 485.58 |
Molecular Formula: | C₂₇H₃₁N₇O₂ |
SMILES: | C=CC(NC1=CC(NC2=NC=CC(C3=CNC4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R/T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively. Phase 1. |
IC50&Target: | |
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References: |
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