Rociletinib
Cat. No. :YN340180
CAS No. :1374640-70-6
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Product Name: | Rociletinib |
CAS NO.: | 1374640-70-6 |
Chemical Name: | |
Synonyms: | CNX-419 |
Molecular Weight: | 555.55 |
Molecular Formula: | C₂₇H₂₈F₃N₇O₃ |
SMILES: | C=CC(NC1=CC=CC(NC2=NC(NC3=CC=C(N4CCN(C(C)=O)CC4)C=C3OC)=NC=C2C(F)(F)F)=C1)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Rociletinib (CO-1686, AVL-301) is an irreversible, mutant-selective EGFR inhibitor with Ki of 21.5 nM and 303.3 nM for EGFRL858R/T790M and EGFRWT in cell-free assays, respectively. Phase 2. |
IC50&Target: | |
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References: |
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