Lazertinib
Cat. No. :YN340066
CAS No. :1903008-80-9
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order@ubiochem.com| Product Name: | Lazertinib |
| CAS NO.: | 1903008-80-9 |
| Chemical Name: | |
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| Molecular Weight: | 554.64 |
| Molecular Formula: | C₃₀H₃₄N₈O₃ |
| SMILES: | C=CC(NC1=CC(NC2=NC=CC(N3N=C(C4=CC=CC=C4)C(CN(C)C)=C3)=N2)=C(OC)C=C1N5CCOCC5)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Lazertinib (YH25448,GNS-1480) is a potent, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively, showing much higher IC50 values aganist ErbB2 and ErbB4. |
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