CP-724714
Cat. No. :YN340159
CAS No. :383432-38-0
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5mg
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Product Name: | CP-724714 |
CAS NO.: | 383432-38-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 469.53 |
Molecular Formula: | C₂₇H₂₇N₅O₃ |
SMILES: | O=C(COC)NC/C=C/C1=CC2=C(N=CN=C2C=C1)NC3=CC=C(C(C)=C3)OC4=CC=C(N=C4)C.[(E)] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | CP-724714 is a potent, selective and orally activeErbB2 (HER2)tyrosine kinase inhibitor, with an IC50 of 10nM. CP-724714 displays a marked selectivity against EGFR kinase (IC50=6400nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities. |
IC50&Target: | |
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References: |
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