TAK-285
Cat. No. :YN340167
CAS No. :871026-44-7
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5mg
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Product Name: | TAK-285 |
CAS NO.: | 871026-44-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 547.96 |
Molecular Formula: | C₂₆H₂₅ClF₃N₅O₃ |
SMILES: | ClC(C=C(NC1=NC=NC2=C1N(CCNC(CC(C)(C)O)=O)C=C2)C=C3)=C3OC4=CC=CC(C(F)(F)F)=C4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1. |
IC50&Target: | |
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References: |
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