Allitinib tosylate
Cat. No. :YN340132
CAS No. :1050500-29-2
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Product Name: | Allitinib tosylate |
CAS NO.: | 1050500-29-2 |
Chemical Name: | |
Synonyms: | AST-6 |
Molecular Weight: | 621.08 |
Molecular Formula: | C₃₁H₂₆ClFN₄O₅S |
SMILES: | FC1=CC=CC(COC2=C(Cl)C=C(NC3=NC=NC4=C3C=C(NC(C=C)=O)C=C4)C=C2)=C1.O=S(C5=CC=C(C)C=C5)(O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases. |
IC50&Target: | |
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References: |
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